Natalie Portman ventures into the unknown as a biologist who encounters a strange being in sci-fi film ‘Annihilation.’ (Photo: ScreenCap)

Natalie Portman wants a piece of whatever causes her husband to disappear in a mysterious environmental disaster zone known as “Area X” in a new trailer for the upcoming sci-fi movie “Annihilation.”

The science fiction thriller film is directed and written by Alex Garland based on Jeff VanderMeer’s best-selling book by the same name.

Portman’s character, Lena is joined by Jennifer Jason Leigh a Psychologist, Gina Rodriguez as Anya Thorensen, an anthropologist, Tessa Thompson, a surveyor, and Oscar Isaac as Lena’s biologist husband.

Lena leads an expedition into the environmental disaster zone, not knowing quite what to expect. What she finds is something not out of this world, but of it. But not what she ever expected.

Her group makes up the 12th expedition into the area. The others have all ended in disaster. Her husband was part of the 11th expedition.

He disappears, but suddenly reappears in the kitchen of his home with no idea how he got there. Before, Lena can figure things out, he dies of cancer.

Other members of the 11th expedition face a similar fate.

The film is set for release on Feb. 23, 2018.

Check out the trailer below.